ESTRAMUST-2 READY

Hycedil NCR 10

ESTRAMUST-2 READY

Estramust-2 is a hormone replacement therapy used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate. Menopause is the stopping of a woman’s period for life and is marked after an entire span of 12 months without periods.

Estramust-2 is composed of Estradiol valerate that works by enhancing the lowered levels of the sex hormone oestrogen in the peri or post-menopausal female body. This helps combat the various symptoms of menopause such as vaginal dryness, hot flashes (hot face, neck and chest) and weak bones.

Take Estramust-2 as prescribed. In some cases, Estramust-2 may cause certain common side effects such as nausea, vomiting, breast soreness, headache and bloating. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Keep your doctor informed if you are allergic to any medicines. Discuss with the doctor if you have/had cardiovascular disease, thrombotic disorders, pulmonary embolism, mental health disorders, liver disease, gall bladder disease, anaemia, bleeding disorders, or breast/uterine/cervical cancer. Estramust-2 is intended for post-menopausal women; therefore, do not take Estramust-2 if you are pregnant or breastfeeding.

Uses:Treatment of Post-menopausal symptoms, Osteoporosis, Hypoestrogenism and Advanced androgen-dependent carcinoma of the prostate

Medicinal Benefits

Estramust-2 is a hormone replacement therapy (HRT) used in the treatment of the symptoms of menopause, osteoporosis, hypoestrogenism due to hypogonadism, and advanced androgen-dependent carcinoma of the prostate. Estramust-2 helps in the synthesis and maintenance of sex hormone oestrogen in the body, by acting as its precursor. It acts directly on plasma membrane receptors and promotes the conversion of oestradiol to its most potent counterpart, thereby enhancing the body’s levels of oestrogen and helping fight the symptoms of menopause.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight.

Side Effects

Drug Warnings

Estramust-2 should not be used in case of any known allergy to any of the components. Inform your doctor if you have/had arterial or thrombotic disorders, cardiovascular health disorders,porphyria, anaemia, hypertension, diabetes, asthma, epilepsy, bleeding disorders, liver problem, kidney problem, depression, gallbladder disease, breast/uterine/cervical cancer or any hormone-sensitive cancer. Estramust-2 is intended for use in postmenopausal women, do not take Estramust-2 if you are pregnant or breastfeeding. Estramust-2 should be used with caution if you are on any anti-epileptic, anti-tuberculosis, anti-hypertensive, cardiac, antifungal, antibiotic, anti-depressant or anti-retroviral therapy. Women with a tendency for chloasma/melasma (skin condition commonly seen in middle-aged women), should avoid sun exposure after taking Estramust-2 Women with a history of angioedema should exercise caution while taking Estramust-2 as it may worsen the angioedema.

Drug-Drug Interactions: Estramust-2 is known to interact with antiepileptics (carbamazepine, phenytoin), anti-depressant (St. John’s wort), anti-tuberculosis drug (rifampicin), antibiotics (clarithromycin, erythromycin), antifungals (itraconazole, fluconazole, griseofulvin), cardiac medications(verapamil, diltiazem) and anti-retroviral drugs (ritonavir, nelfinavir, nevirapine) Drug-Food Interactions: Grapefruit juice may interfere with the absorption of Estramust-2. Proceed with caution. Drug-Disease Interactions: Inform your doctor if you have/had breast cancer, cervical cancer, stroke, epilepsy, porphyria, thrombosis, pulmonary embolism, cardiovascular disturbances, gallstones, migraine or any severe headaches, anaemias, bleeding disorders, liver problem, kidney problem, depression, and any other hormone-dependent cancers.

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